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Y Chromosome Deletion Test/ Azoospermia

Y Chromosome Deletion Test/ Azoospermia



A genetic testing to detect the deletions within the male-specific region of the Y-chromosome which cause male infertility.

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Y-Chromosome Deletion Test, Y Chromosome Infertility, Azoospermia, Oligospermia, AZF

Prevalence: Male 1/2,000~1/3,000

Y chromosome microdeletion is a genetic disorders caused by missing gene(s) in the Y chromosome. Many men with Y chromosome microdeletion show no symptoms. It is the most common genetic cause of impaired sperm production and male infertility especially in men with azoospermia (absence of sperm in semen) or severe oligospermia.

ASRM* recommends that Y-chromosome analysis should be offered to all men with nonobstructive azoospermia or severe oligospermia before undergoing ICSI.

*Reference: Fertility and Sterility: Volume 98, Issue 2, August 2012, Pages 294-301


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