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\/>\n\u85c9\u7531\u4e0a\u8ff0\u8fc7\u7a0b\uff0c\u521b\u6e90\u7d2f\u79ef\u4e86150\u4e07\u4eba\u6b21\u62a5\u544a\uff0c\u5e9e\u5927\u7684\u57fa\u56e0\u8d44\u6599\u5e93\uff0c\u6210\u4e3a\u652f\u6301\u4e34\u5e8a\u5224\u8bfb\u7684\u91cd\u8981\u4f9d\u636e\uff0c\u4f5c\u4e3a\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\u3001\u80da\u80ce\u7740\u5e8a\u524d\u57fa\u56e0\u7b5b\u68c0\u7684\u628a\u5173\u8005\uff0c\u6211\u4eec\u4ee5\u53d7\u68c0\u8005\u6700\u7ec8\u53d7\u76ca\u4e3a\u91cd\uff0c\u4e00\u8def\u5e2e\u52a9\u4e34\u5e8a\u7aef\u5f97\u5230\u6700\u597d\u7ed3\u679c\uff0c\u7ecf\u7531\u591a\u65b9\u6bd4\u5bf9\uff0c\u59a5\u5584\u53d1\u6325\u5404\u9879\u68c0\u6d4b\u7684\u957f\u5904\uff0c\u8fd0\u7528\u8ffd\u8e2a\u5206\u6790\u8865\u8db3\u4e0d\u540c\u68c0\u6d4b\u4e4b\u95f4\u7684\u6781\u9650\uff0c\u5982\u540cNIPT\u3001\u7f8a\u6c34\u6838\u578b\u5206\u6790\u548cSNP\u7f8a\u6c34\u6676\u7247\u7684\u7efc\u5408\u5224\u65ad\u3002<\/p>\n<p>\u3010\u95f4\u8d28\u5e72\u7ec6\u80de(MSC)\u4e4b\u514d\u75ab\u8c03\u8282\u673a\u5236\u7684\u591a\u5143\u5e94\u7528\u5f00\u53d1\u3011<br \/>\n\u8fc7\u53bb3\u5e74\uff0c\u9646\u7eed\u6709\u51e0\u4e2a\u9ad8\u9f84\u957f\u8005\u672c\u5df2\u88ab\u533b\u5e08\u5ba3\u5224\u8981\u622a\u80a2\uff0c\u8fd8\u597d\u300a\u7279\u7ba1\u6cd5\u300b\u5f00\u653e\uff0c\u4ed6\u4eec\u5f97\u4ee5\u4f7f\u7528\u81ea\u4f53\u7684\u8102\u80aa\u95f4\u8d28\u5e72\u7ec6\u80de\uff0c\u52a0\u901f\u4f24\u53e3\u6108\u5408\uff0c\u770b\u523080\u5c81\u7684\u75c5\u60a3\u4f24\u53e3\u957f\u51fa\u5e74\u8f7b\u7684\u76ae\u80a4\uff0c\u53e6\u4e00\u4e2a\u751a\u81f3\u672c\u6765\u4f24\u53e3\u6df1\u53ef\u89c1\u9aa8\uff0c6\u4e2a\u6708\u540e\u6539\u5584\u4e8695%\uff0c\u8fd9\u4e00\u6b65\uff0c\u8baf\u8054\u6574\u6574\u82b1\u4e8620\u5e74\u3002<br \/>\n\u4ece1990\u5e74\u5f00\u59cb\uff0c\u6211\u5728\u7f8e\u56fd\u535a\u58eb\u73ed\u671f\u95f4\uff0c\u4f01\u56fe\u627e\u5230\u6700\u597d\u7684\u6750\u6599\uff0c\u6211\u4eec\u4ee5\u4e3a\u94bb\u77f3\u5c31\u662f\u6750\u6599\u79d1\u5b66\u754c\u7684\u5723\u676f\u3002\u5b66\u6821\u5e2e\u5fd9\u7533\u8bf7\u5230\u4e13\u5229\uff0c\u9001\u4ea4\u5404\u884c\u5404\u4e1a\u5bfb\u6c42\u56de\u9988\u3002\u7ed3\u679c\u5e76\u975e\u4e09\u5927\u6c7d\u8f66\u5382\u3001\u7cbe\u5bc6\u5382\u3001\u534a\u5bfc\u4f53\u5382\uff0c\u53cd\u800c\u662f\u5168\u7403\u4e00\u4e2a\u5fc3\u810f\u74e3\u819c\u6700\u77e5\u540d\u7684\u516c\u53f8Medtronic\u7b2c\u4e00\u4e2a\u56de\u8986\uff1a\u60f3\u5c06\u94bb\u77f3\u8584\u819c\u7528\u5728\u5fc3\u810f\u74e3\u819c\u4e0a\u9762\uff01\u540e\u6765\u6211\u770b\u5230\u6bd4\u94bb\u77f3\u66f4\u5b8c\u7f8e\u7684\u6750\u6599\uff1a\u5e72\u7ec6\u80de\uff01\u5b83\u53ef\u4ee5\u94bb\u8fdb\u5b54\u72b6\u7ed3\u6784\uff0c\u7136\u540e\u5408\u4e3a\u4e00\u4f53\uff0c\u800c\u4e14\u4fdd\u6709\u6d3b\u6027\uff0c\u5c31\u4e00\u5934\u683d\u8fdb\u4e86\u5e72\u7ec6\u80de\u518d\u751f\u533b\u5b66\u7684\u9886\u57df\u3002<br \/>\n2002\u5e74\uff0c\u6211\u9080\u8bf7\u5f53\u4ee3\u5e72\u7ec6\u80de\u7814\u7a76\u7684\u4e13\u5bb6John E.Wagner(\u7ea6\u7ff0\u534e\u683c\u7eb3\u6559\u6388)\uff0c\u5230\u53f0\u6e7e\u6765\u5206\u4eab\u5e72\u7ec6\u80de\u79fb\u690d\u7ecf\u9a8c\uff0c\u4ed6\u5b8c\u5168\u8ba4\u540c\u95f4\u8d28\u5e72\u7ec6\u80de\u672a\u6765\u524d\u666f\u65e0\u9650\u3002\u8baf\u8054\u4ece2005\u5e74\u8d77\u5f00\u59cb\u5efa\u7f6e\u4e00\u4e2a\u5e9e\u5927\u7684\u95f4\u8d28\u5e72\u7ec6\u80de(MSC)\u8d44\u6599\u5e93\uff0c\u540c\u65f6\u51b3\u5b9a\u6295\u5165\u4f24\u53e3\u6108\u5408\u7814\u7a76\u30012007\u5e74\u52a8\u7269\u5b9e\u9a8c\u3002<br \/>\n\u8baf\u80542002\u5e74\u51b3\u5b9a\u6295\u5165\u95f4\u8d28\u5e72\u7ec6\u80de(MSC)\u65f6\uff0c\u56e0\u4e3a\u770b\u5230\u514d\u75ab\u8c03\u8282\u7684\u91cd\u8981\u673a\u5236\uff0c\u56e0\u6b64\u5f80\u540e\u4e0d\u7ba1\u6069\u6148\u7597\u6cd5\u3001Phase \u2160\u3001Phase \u2161\u3001\u7279\u7ba1\u6cd5\u3001\u518d\u751f\u533b\u7597\u4e09\u6cd5\uff0c\u53ea\u8981\u7b26\u5408\u533b\u5b66\u4f26\u7406\uff0c\u90fd\u5728\u8baf\u8054\u7684\u84dd\u56fe\u4e0a\u3002<br \/>\n\u8baf\u8054\u6700\u65e9\u662f\u4e0e\u8840\u6db2\u80bf\u7624\u79d1\u5408\u4f5cGvHD(\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75be\u75c5)\uff0c\u5c06\u95f4\u8d28\u5e72\u7ec6\u80de\u8ddf\u9020\u8840\u5e72\u7ec6\u80de\u5171\u540c\u79fb\u690d\u3002\u9646\u7eed\u53d1\u88684\u7bc7paper\u540e\uff0c\u513f\u79d1\u4e5f\u627e\u8baf\u8054\u505a\u80ba\u90e8\u5404\u79cd\u635f\u4f24\u75be\u75c5\uff0c\u8baf\u8054\u66fe\u6210\u529f\u6551\u52a9\u4e00\u4e2a\u751f\u75c5\u5782\u5371\u7684\u65b0\u751f\u547d\uff0c\u4f7f\u5176\u4ece\u652f\u6c14\u7ba1\u80ba\u53d1\u80b2\u4e0d\u5168(BPD)\u7684\u75c7\u72b6\uff0c\u8f6c\u6210\u4e00\u4e2a\u5065\u5eb7\u7684\u5b9d\u5b9d\u3002\u5728\u300aPEDIATRICS\u300b\u53d1\u8868\u540e\uff0c\u80f8\u8154\u79d1\u6025\u91cd\u75c7\u7684ARDS(\u6025\u6027\u547c\u5438\u7a98\u8feb\u75c7\u5019\u7fa4)\u4e5f\u5f00\u59cb\u627e\u8baf\u8054\u5408\u4f5c\u3002<br \/>\n\u540e\u6765\u4e5f\u8ddf\u7f8e\u56fd\u8f9b\u8f9b\u7eb3\u63d0\u5927\u5b66\u3001\u6797\u53e3\u957f\u5e9a\u3001\u53f0\u5927\u5171\u540c\u5408\u4f5c\u773c\u89d2\u819c\u6cbb\u7597\uff0c\u4e0e\u70e7\u70eb\u4f24\u4e2d\u5fc3\u5408\u4f5c\u76ae\u80a4\u7684\u53d1\u708e\u53cd\u5e94\u3001\u6162\u6027\u4f24\u53e3\u6108\u5408\u3002\u63a5\u4e0b\u6765OA(\u9000\u5316\u6027\u5173\u8282\u708e)\uff0c\u8baf\u8054\u4ee5MSC\u7684\u514d\u75ab\u8c03\u8282\u7684\u6838\u5fc3\u673a\u5236\uff0c\u5728\u5404\u9886\u57df\u540c\u6b65\u5c55\u5f00\u5e73\u884c\u7684\u4e13\u6848\u7814\u7a76\u3002<br \/>\n\u4ece\u81ea\u4f53\u76f8\u5173\u7684\u76ae\u80a4\u514d\u75ab\u75be\u75c5\u3001\u80ba\u90e8\u7ea4\u7ef4\u5316\uff0c\u751a\u81f3\u50cfCOVID-19\u5f15\u8d77\u7684\u6025\u6027\u547c\u5438\u7a98\u8feb\u75c7\u5019\u7fa4(ARDS)\uff0c\u6cbb\u7597\u80fd\u5982\u6b64\u6210\u529f\uff0c\u771f\u7684\u8981\u5f52\u529f\u5f53\u65f6Phase \u2160 GvHD\u7684\u7814\u7a76\u4ee5\u53caPhase \u2160 ARDS\u7684\u57fa\u7840\u3002\u4e0b\u4e00\u6b65\u5c31\u662f\u63a2\u7d22\u7ec6\u80de\u5236\u5242\uff0c\u56e0\u6b64\u8baf\u8054\u6210\u7acb\u4e86\u65b0\u516c\u53f8\uff0c\u5f00\u59cb\u6295\u51656\u79cd\u7ec6\u80de\u5236\u5242\u7684\u5f00\u53d1\u3002<br \/>\n\u8baf\u8054\u4ece2015\u5e74\u5c31\u5f00\u59cb\u5c06\u7ec6\u80de\u7684exosome(\u5916\u6ccc\u4f53)\u3001cytokine\uff0c\u5e94\u7528\u5728\u91cd\u5927\u75be\u75c5\u7684\u6162\u6027\u4f24\u53e3\u3001\u598a\u5a20\u7eb9\u53ca\u5176\u4ed6\u7684\u76ae\u80a4\u6cbb\u7597\u5e94\u7528\uff0c\u751a\u81f3\u6bdb\u53d1\uff0c\u66f4\u62d3\u5c55\u5230CDMO\u59d4\u6258\u5236\u9020\u7814\u53d1\u7684\u9886\u57df\u3002<br \/>\n\u8baf\u8054\u56de\u987e\u8fc7\u53bb23\u5e74\uff0c\u771f\u7684\u662f\u65e0\u754c\u9650\u7684\u8de8\u754c\uff0c\u5fc3\u4e2d\u65e0\u754c\uff0c\u53ef\u4ee5\u66f4\u81ea\u7531\u7684\u4e00\u8d77\u6765\u8ffd\u5bfb\uff0c\u7ec6\u80de\u6cbb\u7597\u8ddf\u7cbe\u51c6\u5065\u5eb7\u7684\u7f8e\u597d\u8de8\u754c\u3002<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><style>@media (min-width: 768px) { .liquid-row-responsive-69f8b7bd045ee {padding-top:10px !important;  }  } @media (min-width: 992px) { .liquid-row-responsive-69f8b7bd045ee {padding-top:10px !important;  }  } @media (min-width: 1200px) { .liquid-row-responsive-69f8b7bd045ee {padding-top:10px !important;  }  }   <\/style><section class=\"vc_row wpb_row vc_row-fluid vc_custom_1618827351209 row-contains-padding-top liquid-row-responsive-69f8b7bd045ee liquid-row-shadowbox-69f8b7bd0460a\"><div class=\"ld-container container\"><div class=\"row ld-row\"><div class=\"wpb_column vc_column_container vc_col-sm-2 liquid-column-69f8b7bd048a7\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"   ><div class=\"wpb_wrapper-inner\"><\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container vc_col-sm-8 liquid-column-69f8b7bd04ab8\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"   ><div class=\"wpb_wrapper-inner\"><\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container vc_col-sm-2 liquid-column-69f8b7bd04cbc\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"   ><div class=\"wpb_wrapper-inner\"><\/div><\/div><\/div><\/div><\/div><\/div><\/section><style>@media (min-width: 768px) { .liquid-row-responsive-69f8b7bd04ec3 {margin-top:-50px !important;  }  } @media (min-width: 992px) { .liquid-row-responsive-69f8b7bd04ec3 {margin-top:-50px !important;  }  } @media (min-width: 1200px) { .liquid-row-responsive-69f8b7bd04ec3 {margin-top:-50px !important;  }  }   <\/style><section class=\"vc_row wpb_row vc_row-fluid vc_custom_1618902491986 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